HTS Equipment

Over the last few years, we have established two HTS systems use state-of-the-art liquid handlers and multi-mode plate readers. All liquid handlers and readers are either integrated in the full HTS system or setup for stand-alone use with automated plate stackers. Our liquid handling capacities allow us to perform liquid transfer from 25nL to 1000ul between 96 well plates to 1536 well plates. We have several plate readers that can measure all common modalities including absorbance, fluorescence, FP, TRF, TR-FRET, Alpha screen, luminescence, etc.

Liquid Handlers

INSTRUMENT MANUFACTURER TYPE OPTIONS OTHER INFO IMAGE
 Mosquito X1 TTPTech Automated Cherry picking DMSO or aqueous solvents
cherry-picking, Volumes: 25 – 1200 nL
96, 384, 1536-well plates
 Bravo Velocity 11/Agilent Automated Pipette Liquid Transfer Any liquid viscosity. Plate stamping and serial dilutions (row or column), Cherry picking, Volumes: 0.1 – 250 uL 96, 384, 1536-well plates
 VPrep Velocity 11/Agilent Automated Pipette Liquid Transfer Any liquid viscosity. Plate stamping Volumes: 1 – 300 uL 96, 384, 1536-well plates
 Felix Cybio Automated Pipette Liquid Transfer Any liquid viscosity. Plate stamping and serial dilutions (row or column), Cherry picking, Volumes: 0.1 – 250 uL 96, 384, 1536-well plates
 Well Vario Cybio Automated Pipette Liquid Transfer Variable liquid viscosities. Plate stamping. Fix volumnes: 25 or 100nl 384, 1536-well plates
 EVO100 Tecan Automated Pipette Liquid Transfer Any liquid viscosity. Plate stamping and serial dilutions, Cherry picking, Volumes: 0.5 – 1000 uL 96 or 384-well plates
 Biomek NXP Beckman Automated Pipette Liquid Transfer Any liquid viscosity. Plate stamping and serial dilutions (row or column), Cherry picking, Volumes: 0.5 – 250 uL 384, 1536-well plates
 Versette Thermo Automated Pipette Liquid Transfer Any liquid viscosity. Plate stamping. Volumes: 0.5 – 250 uL 96 well plates

Plate Readers

INSTRUMENT MANUFACTURER TYPE OPTIONS OTHER INFO IMAGE
 H1MF Biotek Multimode iterative well scanning FI, Lum, UV/VIS, FP, TRF 96, 384, 1536-well plates
 VarioSkan flash Thermo Multimode iterative well scanning FI, Lum, UV/VIS, TRF 96, 384, 1536-well plates
 CLARIOstar BMGlabTech Multimode iterative well scanning FI, Lum, UV/VIS, FP, TRF, TR-FRET, AS 96, 384, 1536-well plates
 PHERAstar FSX BMGlabTech Multimode iterative well scanning FI, Lum, UV/VIS, FP, TRF, TR-FRET, AS 96, 384, 1536-well plates
 Cytation 5 Biotek Multimode iterative well scanning FI, Lum, UV/VIS, FP, TRF, TR-FRET, AS 96, 384, 1536-well plates

Washers and Dispensors

INSTRUMENT MANUFACTURER TYPE OPTIONS OTHER INFO IMAGE
 Combi Thermo Liquid Dispenser Variable liquid viscosities
High-speed 8-channel liquid dispenser using a peristaltic pump
Volumes: 0.5 – 2500 uL
96, 384, 1536-well plates
 MultiFlo FX(2) Biotek Liquid Dispenser with washer module Variable liquid viscosities
High-speed 8-channel liquid dispenser using two peristaltic pump
Volumes: 1 – 2500 uL
96, 384, 1536-well plates
 405TS (2) Biotek Plate Washer Variable liquid viscosities
Plate washer- 96 well manifold
Volumes: 50 – 3000 uL.
96, 384 well plates
 EL406 (3) Biotek Plate Washer/Dispenser Variable liquid viscosities
Plate washer- 96-192 well manifold
Volumes: 50 – 3000 uL. One peristaltic pump and two syringe pumps
96, 384, 1536-well plates
 Mantis Formulatrix Single channel dispenser Variable liquid viscosities single channel liquid dispenser.  Volumes: 0.1 – 400uL 96, 384, 1536-well plates

Compounds/Sample storage

Automated Western Blots

Various Imagers

RT-PCR

MAGPIX Multiplexing Immunoassay system